Is synthetic substance P algogenic in the dog?
نویسندگان
چکیده
منابع مشابه
Substance P in ovarian carcinoid.
A high content of substance P (124 ng/g wet tissue) was demonstrated by radioimmunoassay in lymph node metastases in a patient with bilateral ovarian carcinoid tumours. The plasma substance P level was elevated but urinary 5-hydroxyindoleacetic acid (5-HIAA) was low. It is suggested that, in some carcinoid patients, an elevated plasma substance P level may help diagnosis and follow-up when urin...
متن کاملMetabolic fate of a synthetic corticosteroid (triamcinolone) in the dog.
Triamcinolone (9cu-fluoro-1 1/3,1601,17a, 21-tetrahydroxy-l , 4pregnadiene-3,20-dione) is one of several derivatives of hydrocortisone widely used in medical practice. It differs from hydrocortisone in the presence of the Al-double bond and the Sac-fluoro and lba-hydroxyl substituents. The effects of these and other substituents on the rate of metabolism by rat liver preparations (2), on bindin...
متن کاملConformational Studies of Synthetic Polyethylene Glycol Bound Substance P and its Lower Analogues
The synthesis o f Substance P (SP) bound at the C-terminal methionine to polyethylene glycol monomethyl ether (M -PEG ) is described. SP-PEG-M is obtained in good yield by the liquidphase peptide synthesis. Gel permeation chromatography reveals that aggregated forms of the PEG-bound peptides are absent in CHC13. CD and IR spectra point to a /3-turn located at the Nterminal part o f SP-PEG-M . I...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1975
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)65456-9